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Distance: 12,798.63km
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Major types of Prostanoid Receptor E-type prostanoid (EP) receptors are an important class of prostanoid receptor termed EP1 EP2 EP3 and EP4. EP1 was the first reported EP receptor and was found in kidney and lung tissue at a low level. The human EP1 receptor is composed of 402 amino acids sharing a sequence homology of 86% with the rat EP1 receptor. EP2 and EP4 have the similarities in pharmacology and functional coupling mediating celluar signaling via adenylate cyclase activity. The EP3 receptor is reported to have various isoforms that differ in the amino acid sequence of the C-terminal region.... read more
Major types of Prostanoid Receptor E-type prostanoid (EP) receptors are an important class of prostanoid receptor termed EP1 EP2 EP3 and EP4. EP1 was the first reported EP receptor and was found in kidney and lung tissue at a low level. The human EP1 receptor is composed of 402 amino acids sharing a sequence homology of 86% with the rat EP1 receptor. EP2 and EP4 have the similarities in pharmacology and functional coupling mediating celluar signaling via adenylate cyclase activity. The EP3 receptor is reported to have various isoforms that differ in the amino acid sequence of the C-terminal region.... read more
Distance: 12,798.63km
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Major types of Tau Normal Tau protein can be divided into two kinds one is in the central nervous system (molecular weight 4500~6000) known as low molecular weight Tau (LMW-Tau). The other is found in the peripheral nervous system (about 9000 molecular weight) and is called high molecular weight Tau(HMW-Tau). Tau proteins are encoded by genes located on the long arm of chromosome 17. Because of the differences in mRNA of transcription products during post-transcriptional shearing and modification 6 isomers can be formed which are named Tau1~Tau6 respectively. They differ in the carboxyl terminal of 3R(3R-Tau) or 4R(4R-Tau). The six... read more
Major types of Tau Normal Tau protein can be divided into two kinds one is in the central nervous system (molecular weight 4500~6000) known as low molecular weight Tau (LMW-Tau). The other is found in the peripheral nervous system (about 9000 molecular weight) and is called high molecular weight Tau(HMW-Tau). Tau proteins are encoded by genes located on the long arm of chromosome 17. Because of the differences in mRNA of transcription products during post-transcriptional shearing and modification 6 isomers can be formed which are named Tau1~Tau6 respectively. They differ in the carboxyl terminal of 3R(3R-Tau) or 4R(4R-Tau). The six... read more
Distance: 12,798.63km
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Antagonist of CD88 PMX 205 trifluoroacetate is an effective complement C5a receptor (C5aR; CD88) antagonists. W-54011 is an oral effective specific CD88 (C5a receptor) antagonist inhibiting the binding of 125i-labeled C5a to human neutrophilic granulocytes Ki = 2.2 nm. CD88 and diseases CD88 also known as C5aR is expressed in the parenchyma of human and rodent especially liver parenchyma cells lung smooth muscle cells lung capillary endothelial cells bronchial epithelial cells and alveolar epithelial cells. It is involved in a series of inflammatory processes and plays an important role in the pathophysiological processes such as acute lung injury sepsis rheumatoid... read more
Antagonist of CD88 PMX 205 trifluoroacetate is an effective complement C5a receptor (C5aR; CD88) antagonists. W-54011 is an oral effective specific CD88 (C5a receptor) antagonist inhibiting the binding of 125i-labeled C5a to human neutrophilic granulocytes Ki = 2.2 nm. CD88 and diseases CD88 also known as C5aR is expressed in the parenchyma of human and rodent especially liver parenchyma cells lung smooth muscle cells lung capillary endothelial cells bronchial epithelial cells and alveolar epithelial cells. It is involved in a series of inflammatory processes and plays an important role in the pathophysiological processes such as acute lung injury sepsis rheumatoid... read more
Distance: 12,798.63km
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Peptide is a product of protein hydrolysis. After being degraded by enzymes the protein ingested by the human body is mainly digested and absorbed in the form of peptides. The peptide in the body can regulate the physiological functions of all cells and can provide nutrients to the body. The composition is basically the same and the peptide has a more stable processing property and a more absorbing victory property than the protein which will greatly broaden the application range of the protein. The relationship between structure and function of peptides is well reflected in the development of peptide drugs.... read more
Peptide is a product of protein hydrolysis. After being degraded by enzymes the protein ingested by the human body is mainly digested and absorbed in the form of peptides. The peptide in the body can regulate the physiological functions of all cells and can provide nutrients to the body. The composition is basically the same and the peptide has a more stable processing property and a more absorbing victory property than the protein which will greatly broaden the application range of the protein. The relationship between structure and function of peptides is well reflected in the development of peptide drugs.... read more
Distance: 12,798.63km
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
A formulation contains the active pharmaceutical ingredient (API) and other inactive excipients. • Firstly excipient compatibility studies. Aiming to select viable excipients that are chemically and physically compatible with the API(s). The excipients selected during the excipient compatibility study are incorporated into the process feasibility study using DOE. • Next selecting the final excipients and define the optimal levels for all excipients in the formulation. • Finally designing and conduct a formulation optimization study to optimize the excipient levels in the final formulation system. Creative Peptides offers design and optimization of formulations from early pre-clinical stage to Phase I and... read more
A formulation contains the active pharmaceutical ingredient (API) and other inactive excipients. • Firstly excipient compatibility studies. Aiming to select viable excipients that are chemically and physically compatible with the API(s). The excipients selected during the excipient compatibility study are incorporated into the process feasibility study using DOE. • Next selecting the final excipients and define the optimal levels for all excipients in the formulation. • Finally designing and conduct a formulation optimization study to optimize the excipient levels in the final formulation system. Creative Peptides offers design and optimization of formulations from early pre-clinical stage to Phase I and... read more
Distance: 12,798.63km
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Creative Peptides provides a one-stop solution for all of your peptide-drug bioconjugation needs. Our custom peptide synthesis modification and conjugation services involve chemical modification of peptide at highly specific sites. This allows for the elegant attachment of drugs or bioactive molecules though a wide variety of coupling techniques. Creative Peptides gives you the best quality in peptides bioconjugation chemistry in the industry by implementing our state-of-the art peptides synthesis platform. Peptide synthesis modifications and conjugates produced at Creative Peptides have substantial purity. Each peptide-drug conjugate is meticulously monitored during synthesis and controlled according to our quality assurance and quality control... read more
Creative Peptides provides a one-stop solution for all of your peptide-drug bioconjugation needs. Our custom peptide synthesis modification and conjugation services involve chemical modification of peptide at highly specific sites. This allows for the elegant attachment of drugs or bioactive molecules though a wide variety of coupling techniques. Creative Peptides gives you the best quality in peptides bioconjugation chemistry in the industry by implementing our state-of-the art peptides synthesis platform. Peptide synthesis modifications and conjugates produced at Creative Peptides have substantial purity. Each peptide-drug conjugate is meticulously monitored during synthesis and controlled according to our quality assurance and quality control... read more
Distance: 12,798.63km
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Creative Peptides has developed a reliable procedure for SAR analysis of peptides we can provide global customers with the analysis of peptides based on our excellent technology. The 3D-QSAR method used by Creative Peptides is more physicochemically meaningful and can indirectly reflect the non-bond interaction characteristics between the peptide and the target. Creative Peptides uses a method of comparative molecular similarity indices analysis (CoMSIA) for peptide analysis the steps of which include: Determining the active conformation of a peptide: the optimal conformation of a peptide is obtained by molecular mechanics or quantum chemical procedures. Molecular superposition: the optimal conformation of... read more
Creative Peptides has developed a reliable procedure for SAR analysis of peptides we can provide global customers with the analysis of peptides based on our excellent technology. The 3D-QSAR method used by Creative Peptides is more physicochemically meaningful and can indirectly reflect the non-bond interaction characteristics between the peptide and the target. Creative Peptides uses a method of comparative molecular similarity indices analysis (CoMSIA) for peptide analysis the steps of which include: Determining the active conformation of a peptide: the optimal conformation of a peptide is obtained by molecular mechanics or quantum chemical procedures. Molecular superposition: the optimal conformation of... read more
Distance: 12,798.63km
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Tel: 6316197922
The advantage of PMF is that if the protein is present in the protein database only the mass of the protein peptide is known and it takes no time to perform DEVONO sequencing. However PMF-based protein identification relies on a single protein because mixed proteins can significantly complicate PMF analysis and may yield incorrect results. Therefore for PMF identification with more than 2-3 protein samples additional MS/MS-based protein identification is required to enhance the specificity of protein identification. Our Services Identification of protein gel sample Creative Peptides accepts samples of various types of dyed protein tapes including Camas Bright Blue... read more
Tel: 6316197922
The advantage of PMF is that if the protein is present in the protein database only the mass of the protein peptide is known and it takes no time to perform DEVONO sequencing. However PMF-based protein identification relies on a single protein because mixed proteins can significantly complicate PMF analysis and may yield incorrect results. Therefore for PMF identification with more than 2-3 protein samples additional MS/MS-based protein identification is required to enhance the specificity of protein identification. Our Services Identification of protein gel sample Creative Peptides accepts samples of various types of dyed protein tapes including Camas Bright Blue... read more
Distance: 12,798.63km
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Tel: 1631619792
Our Services Extraction of peptides: protease inactivation Pretreatment: removal of protein Peptide purification: chromatography capillary gel Peptide identification: MALDI-TOF-MS LC-MS CE-MS Peptide quantification: immunoassay isotope mass shift By removing all proteins in biological samples body fluids and tissue extracts by size exclusion chromatography LC-MS-based assays can be quickly established and validated to identify peptides with high precision and repeatability. After a detailed and comprehensive discussions with customers we will provide you with a peptide set research and analysis services tailored. Creative Peptides has successfully developed a reliable method for the analysis of peptides by using several of the peptide analysis... read more
Tel: 1631619792
Our Services Extraction of peptides: protease inactivation Pretreatment: removal of protein Peptide purification: chromatography capillary gel Peptide identification: MALDI-TOF-MS LC-MS CE-MS Peptide quantification: immunoassay isotope mass shift By removing all proteins in biological samples body fluids and tissue extracts by size exclusion chromatography LC-MS-based assays can be quickly established and validated to identify peptides with high precision and repeatability. After a detailed and comprehensive discussions with customers we will provide you with a peptide set research and analysis services tailored. Creative Peptides has successfully developed a reliable method for the analysis of peptides by using several of the peptide analysis... read more
Distance: 12,798.63km
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Tel: 6316197922
Creative Peptides have many years of experience in peptide synthesis and our chemical synthesis team will build production solutions based on customer needs. Our expertise in the custom synthesis of peptides allows us to produce large-scale high-quality peptides which with high success rates and good purity covering a wide range of peptides in research production etc. Cost analysis project review process optimization and quality control reports are delivered to our customers in a timely manner to ensure that you get the most satisfactory peptide products. Service Features: • Development and optimization of production processes • Efficient production • Flexible tailor-made... read more
Tel: 6316197922
Creative Peptides have many years of experience in peptide synthesis and our chemical synthesis team will build production solutions based on customer needs. Our expertise in the custom synthesis of peptides allows us to produce large-scale high-quality peptides which with high success rates and good purity covering a wide range of peptides in research production etc. Cost analysis project review process optimization and quality control reports are delivered to our customers in a timely manner to ensure that you get the most satisfactory peptide products. Service Features: • Development and optimization of production processes • Efficient production • Flexible tailor-made... read more
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