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7,171 RESULTS WITHIN anywhere FROM https:, United States
Penicillin-binding proteins Inhibitor
Distance: 12,798.63km
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Tel: 6316197922
An overview of penicillin-binding proteins (PBPs) Penicillin-binding proteins (PBPs) are membrane proteins located on the bacterial cell membrane that can bind covalently to penicillin and non-β-lactam antibiotics. PBPs are enzymes involved in the biosynthesis of bacterial cell wall peptidoglycans including transpeptidase carboxypeptidase and endopeptidase. Its normal existence is an essential condition for bacteria to maintain normal morphology and function. PBPs weigh about 1% of the entire cell membrane and the molecular mass is generally 34.7 to 138.9 ku. Most bacterial cells contain between 10 000 and 10 000 PBPs one of which usually contains 4 to 8 PBPs and different... read more
MHC Peptide
Distance: 12,798.63km
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Tel: 6316197922
Creative Peptides has launched a series of MHC-peptide Tetramers which are ready-to-use reagents conjugated to a fluorochrome group such as Brilliant Violet 421(BV421) phycoerythrin (PE) or allophycocyanin (APC). In 1996 the development of reagents consisting of soluble MHC class I–peptide complexes which was applied to detect CD8+ cells by flow cytometry had effectively promoted a revolution of antigen-specific T cells. Traditionally TCR (T cell receptor) has a low avidity and fast off-rate for MHC-peptides complexes recombinant soluble monomeric MHC-peptide complexes have not been used to detect antigen-specific T cells. Recently Stanford University School of Medicine has presented MHC-peptides tetrameric complexes... read more
Corticotropin
Distance: 12,798.63km
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Tel: 6316197922
Corticotropin (ACTH or adrenocorticotropic hormone) is a polypeptide hormone produced and secreted by the pituitary gland. It is an important player in the hypothalamic-pituitary-adrenal axis. Synonyms/AliasAdrendcorticotrophic hormone;ACTH;ACTH (1-39);Acthar;Adrenocorticotrophin;Adrenocorticotropic hormone;Corticotrophin;H.P. acthar gel Molecular FormulaC207H308N56O58S M.W/Mr.4541.06582 SequenceSYSMEHFRWGKPVGKKRRPVKVYPNGAEDESAEAFPLEF Labeling TargetAdrenocorticotropic hormone receptor ApplicationCorticotropin is for use as a diagnostic agent in the screening of patients presumed to have adrenocortical insufficiency. ActivityAgonist Areas of InterestNeurological Disease FunctionsMelanocortin receptor activity... read more
Plecanatide
Distance: 12,798.63km
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Plecanatide CAT#10-101-170 CAS No.467426-54-6 DescriptionPlecanatide is similar to uroguanylin and structurally related to human uroguanylin. Plecanatide acts as a guanylate cyclase-C (GC-C) agonist. Both plecanatide and its active metabolite bind to GC-C and act locally on the luminal surface of the intestinal epithelium to stimulate secretion of intestinal fluid. Synonyms/Alias(3-Glutamic acid(D>E))human uroguanylin (UGN) Molecular FormulaC65H104N18O26S4 M.W/Mr.1681.88626 SequenceH-Asn-Asp-Glu-Cys-Glu-Leu-Cys-Val-Asn-Val-Ala-Cys-Thr-Gly-Cys-Leu-OH Labeling TargetGuanylate cyclase-C (GC-C) ApplicationPlecanatide is used for the treatment of chronic idiopathic constipation (CIC). ActivityAgonist... read more
Cereolysin
Distance: 12,798.63km
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Tel: 1631619792
Cereolysin CAT#10-101-178 CAS No.72270-31-6 Synonyms/AliasCereolysin;HE383245 Molecular FormulaC59H94N16O19S M.W/Mr.1363.53846 SequenceH-Cys-Glu-Arg-Glu-Pyl-Leu-Tyr-Ser-Ile-Asn-OH Publications 1. C-Peptide replacement therapy and sensory nerve function in type 1 diabetic neuropathy 2. Zeta-potential-changing nanoparticles conjugated with cell-penetrating peptides for enhanced transfection efficiency 3. Myotropic activity of allatostatins in tenebrionid beetles 4. Crystal Structure of BamB from Pseudomonas aeruginosa and Functional Evaluation of Its Conserved Structural Features 5. SERS spectrum of the peptide thymosin‐β4 obtained with Ag nanorod substrate... read more
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Solanezumab
Distance: 12,798.63km
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Tel:
Solanezumab CAT#10-101-180 CAS No.955085-14-0 DescriptionSolanezumab is a humanized monoclonal IgG1 antibody which is directed against the mid-domain of the Aβ peptide. By sequestering Aβ shifting equilibria between different species of Aβ and removing small soluble species of Aβ that are directly toxic to synaptic function it may exert benefit. Molecular FormulaC6396H9922N1712O1996S42 M.W/Mr.144000.1g/mol Labeling TargetAmyloid precursor protein (APP) ApplicationSolanezumab or sola binds the amyloid-β peptides that aggregate and form plaques in the brain that are an early pathological feature of Alzheimer's disease. Areas of Interest: Neurological Disease Disease: Alzheimer's disease... read more
Omiganan
Distance: 12,798.63km
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Omiganan CAT#10-101-181 CAS No.204248-78-2 DescriptionOmiganan kills acne causing bacteria by disrupting the bacterial cell membranes. It also is anti-inflammatory specifically reducing bacteria induced inflammation. Molecular FormulaC90H127N27O12 M.W/Mr.1779.14508 SequenceH-Ile-Leu-Arg-Trp-Pro-Trp-Trp-Pro-Trp-Arg-Arg-Lys-NH2 ApplicationFor treatment in bacterial infection and rosacea. Areas of InterestInfection DiseaseCatheter infections; Rosacea; Acne... read more
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Aclerastide
Distance: 12,798.63km
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Tel:
Aclerastide is an angiotensin receptor agonist. It can reduce fibrosis and scarring in the healing wounds. This action is more pronounced with longer administration of the peptide after injury. The action of this peptide is blocked by the AT receptor antagonist d-Ala7-angiotensin(1-7) which suggests that this receptor is involved in the healing responses to exogenous NorLeu3-A(1-7). Aclerastide has the potential in accelerating wound repair and reducing scar formation.... read more
Iseganan
Distance: 12,798.63km
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Tel: 6316197922
Iseganan is a synthetic analog of a peptide and with broad-spectrum antimicrobial activity. It is under development for the prevention of oral mucositis from chemotherapy and radiation therapy. Synonyms/AliasAntimicrobial peptide IB-367; Iseganan [INN]; UNII-Q9SAI36COS; Q9SAI36COS; CHEMBL2110753;... read more
Smith’s Gravel Pit
Distance: 12,798.63km
7120 Sodus Center Rd, Sodus
Tel: 315-483-6510
Smith’s Gravel Pit offers sand gravel topsoil and stone products for residential and commercial applications. When you choose Smith’s Gravel Pit for your next project you can rest assured that you’re getting the highest quality materials and customer service upstate New York has to offer.... read more
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