Impurities
18 RESULTS WITHIN anywhere FROM https:, United States
Distance: 4,204.33km
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
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Profiling and controlling impurities level and their side pharmaceutical effects is crucial in both drug development and manufacturing process as they may affect the efficacy and safety of APIs and then lead to failure in developing a potential drug or meeting the quality standard in production. BOC Sciences manufactures thousands of pharmaceutical impurities degradations metabolites of active pharmaceutical ingredients and excipients in accordance with the guidelines and limits described in the international pharmacopeia monographs for many impurities to serve drug development. In particular BOC Sciences has access to rarely found degradations preparation standards for a number of OTC pharmaceuticals which... read more
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Profiling and controlling impurities level and their side pharmaceutical effects is crucial in both drug development and manufacturing process as they may affect the efficacy and safety of APIs and then lead to failure in developing a potential drug or meeting the quality standard in production. BOC Sciences manufactures thousands of pharmaceutical impurities degradations metabolites of active pharmaceutical ingredients and excipients in accordance with the guidelines and limits described in the international pharmacopeia monographs for many impurities to serve drug development. In particular BOC Sciences has access to rarely found degradations preparation standards for a number of OTC pharmaceuticals which... read more
Distance: 12,798.63km
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Tel:
Triheptanoin is a triglyceride that is used for the treatment of inherited metabolic diseases epilepsy ventricular hypertrophy and myocardial glucose oxidation. You can find this chemical at BOC Sciences. (www.bocsci.com)... read more
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Triheptanoin is a triglyceride that is used for the treatment of inherited metabolic diseases epilepsy ventricular hypertrophy and myocardial glucose oxidation. You can find this chemical at BOC Sciences. (www.bocsci.com)... read more
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Crystallization of target and data collection BOC Sciences has experience in analyzing a wide range of crystal compounds from small organic molecular to heavy metal complexes and also air-sensitive materials. We offer the service of collecting a complete X-ray diffraction data set on crystals based on the method of slow evaporation and cooling vapor and liquid diffusion sitting or hanging drop sublimation and Co-crystallants. You are welcome to send us your crystal compounds. Or our researchers with a high level of expertise in single crystal growth techniques could do the crystallization for your compounds. The physical and chemical properties of... read more
Crystallization of target and data collection BOC Sciences has experience in analyzing a wide range of crystal compounds from small organic molecular to heavy metal complexes and also air-sensitive materials. We offer the service of collecting a complete X-ray diffraction data set on crystals based on the method of slow evaporation and cooling vapor and liquid diffusion sitting or hanging drop sublimation and Co-crystallants. You are welcome to send us your crystal compounds. Or our researchers with a high level of expertise in single crystal growth techniques could do the crystallization for your compounds. The physical and chemical properties of... read more
Distance: 12,798.63km
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Tel:
BOC Sciences also provide labeling services regarding custom synthesis of compounds that containing carbohydrate constituents. Our scientists can synthesis singly labeled multiply labeled and mixed labeled carbohydrates nucleosides and related derivatives. At BOC Sciences we also offer carbohydrates and nucleosides in stock products including monosaccharides enzyme substrates D- and L- sugars oligosaccharides detergents and nucleosides. In additional to the services above BOC Sciences also offers conjugation of carbohydrate with peptides antibodies and proteins. Carbohydrate expertise means quick lead time Custom quantities tailored to your research needs Commitment to providing rare or specialty carbohydrate compounds Discounts on groups of related compounds... read more
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BOC Sciences also provide labeling services regarding custom synthesis of compounds that containing carbohydrate constituents. Our scientists can synthesis singly labeled multiply labeled and mixed labeled carbohydrates nucleosides and related derivatives. At BOC Sciences we also offer carbohydrates and nucleosides in stock products including monosaccharides enzyme substrates D- and L- sugars oligosaccharides detergents and nucleosides. In additional to the services above BOC Sciences also offers conjugation of carbohydrate with peptides antibodies and proteins. Carbohydrate expertise means quick lead time Custom quantities tailored to your research needs Commitment to providing rare or specialty carbohydrate compounds Discounts on groups of related compounds... read more
Distance: 12,798.63km
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
BOC Sciences can provide a number of nucleotide related services including but not limited to: Gene Synthesis and Cloning Service Gene Mutagenesis Service Oligonucleotide Synthesis Service DNA Methylation Analysis Services Plasmid DNA Production Service Gene Expression Service We have lots of compounds in stock and our existing libraries of building blocks alongside with our specialized expertise allow short cut access to any desired novel nucleotide structure. In short we are convinced that our custom nucleotides synthesis service will meet or exceed your expectations. For additional information and for peptide synthesis pricing please contact us!... read more
BOC Sciences can provide a number of nucleotide related services including but not limited to: Gene Synthesis and Cloning Service Gene Mutagenesis Service Oligonucleotide Synthesis Service DNA Methylation Analysis Services Plasmid DNA Production Service Gene Expression Service We have lots of compounds in stock and our existing libraries of building blocks alongside with our specialized expertise allow short cut access to any desired novel nucleotide structure. In short we are convinced that our custom nucleotides synthesis service will meet or exceed your expectations. For additional information and for peptide synthesis pricing please contact us!... read more
Distance: 12,798.63km
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Application Nucleoside analogues are used as antiviral or anticancer agents in medicine. Several analogues of the sugar backbone exist in molecular biology which are more stable alternative nucleoside/nucleotide analogues including LNA morpholino PNA. Dideoxynucleotides are used in sequencing. These nucleotides possess the non-canonical sugar dideoxyribose which lacks 3’ hydroxyl group (which accepts the phosphate) therefore it cannot bond with the next base and terminates the chain. Our Services BOC Sciences is a leading biotechnology company which has years of professional and abundant experience in providing nucleoside synthesis service for customers all over the world. BOC Sciences’s sophisticated equipments advanced technologies... read more
Application Nucleoside analogues are used as antiviral or anticancer agents in medicine. Several analogues of the sugar backbone exist in molecular biology which are more stable alternative nucleoside/nucleotide analogues including LNA morpholino PNA. Dideoxynucleotides are used in sequencing. These nucleotides possess the non-canonical sugar dideoxyribose which lacks 3’ hydroxyl group (which accepts the phosphate) therefore it cannot bond with the next base and terminates the chain. Our Services BOC Sciences is a leading biotechnology company which has years of professional and abundant experience in providing nucleoside synthesis service for customers all over the world. BOC Sciences’s sophisticated equipments advanced technologies... read more
Distance: 12,798.63km
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Tel:
Apoptosis refers to the autonomous orderly programmed cell death of cells controlled by genes to maintain homeostasis and plays an important role in maintaining intracellular homeostasis. There are three main apoptotic pathways: the death receptor pathway the mitochondrial pathway and the endoplasmic reticulum pathway. Each apoptotic pathway is associated with each other and mediates apoptosis.... read more
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Apoptosis refers to the autonomous orderly programmed cell death of cells controlled by genes to maintain homeostasis and plays an important role in maintaining intracellular homeostasis. There are three main apoptotic pathways: the death receptor pathway the mitochondrial pathway and the endoplasmic reticulum pathway. Each apoptotic pathway is associated with each other and mediates apoptosis.... read more
Distance: 12,798.63km
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Tel:
B lymphocytes can directly participate in humoral immune responses as immune effector cells and can also be used as antigen-presenting cells to capture antigens and present them to T lymphocytes. B cells mediate foreign antigen signals and complex biological effects including B cell activation proliferation and differentiation through their surface B cell receptors (BCR). This process involves a series of downstream signal transduction pathways that interweave to form a very complex B cell receptor signal transduction regulatory network. Many non-Hodgkin's lymphomas (NHL) originate from B lymphocytes. B cell receptor (BCR) complexes and their related protein kinases play important roles in... read more
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B lymphocytes can directly participate in humoral immune responses as immune effector cells and can also be used as antigen-presenting cells to capture antigens and present them to T lymphocytes. B cells mediate foreign antigen signals and complex biological effects including B cell activation proliferation and differentiation through their surface B cell receptors (BCR). This process involves a series of downstream signal transduction pathways that interweave to form a very complex B cell receptor signal transduction regulatory network. Many non-Hodgkin's lymphomas (NHL) originate from B lymphocytes. B cell receptor (BCR) complexes and their related protein kinases play important roles in... read more
Distance: 12,798.63km
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Two NF-κB signaling pathways have been identified including classical and non-canonical activation pathways. The classical signaling pathway is mainly triggered by the combination of the ligands and T cell receptor (TCR) B cell receptor (BCR) or toll-like receptor (TLR) - interleukin-1 receptor (IL-1R) family members. And it terminates in the transcription of target genes encoding chemokines cytokines adhesion molecules inflammatory responses and cell survival. When the cells are in a resting state NF-κB usually binds to the inhibitory proteins IκBs (IκBα IκBβ IκBε) and exists in the cytoplasm in an inactive form and the combination of the two masks the... read more
Two NF-κB signaling pathways have been identified including classical and non-canonical activation pathways. The classical signaling pathway is mainly triggered by the combination of the ligands and T cell receptor (TCR) B cell receptor (BCR) or toll-like receptor (TLR) - interleukin-1 receptor (IL-1R) family members. And it terminates in the transcription of target genes encoding chemokines cytokines adhesion molecules inflammatory responses and cell survival. When the cells are in a resting state NF-κB usually binds to the inhibitory proteins IκBs (IκBα IκBβ IκBε) and exists in the cytoplasm in an inactive form and the combination of the two masks the... read more
Distance: 12,798.63km
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Tel:
The p53 gene is an important tumor suppressor gene and its encoded p53 protein plays a key role in cell cycle regulation DNA repair and induction of apoptosis. Mutation of the p53 gene is one of the important factors in tumorigenesis. The p53 gene is mutated in more than 50% of cancer types which causes the p53 signaling pathway to lose the function of cell growth "brakes". The wild-type p53 protein is located at the intersection of the cell signaling and death signaling networks and plays a decisive role in cell growth differentiation senescence stress and apoptosis. At the same... read more
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The p53 gene is an important tumor suppressor gene and its encoded p53 protein plays a key role in cell cycle regulation DNA repair and induction of apoptosis. Mutation of the p53 gene is one of the important factors in tumorigenesis. The p53 gene is mutated in more than 50% of cancer types which causes the p53 signaling pathway to lose the function of cell growth "brakes". The wild-type p53 protein is located at the intersection of the cell signaling and death signaling networks and plays a decisive role in cell growth differentiation senescence stress and apoptosis. At the same... read more
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