Metabolites

Metabolites are the products of enzyme-catalyzed reactions that occur naturally within cells. The term metabolite is usually used to describe small molecules, while broader application is often practiced. Depending on the origin and function, metabolites can be divided into two major categories; namely, Primary and Secondary metabolites. BOC sciences provides high purity metabolites to help your innovative research.

In drug research, it is clearly the case that the potential for pharmacologically active metabolites must be considered. The occurrence of active metabolites among drugs is frequent, consistent with the notion that small alterations in chemical structure of a drug will not necessarily alter its biologic properties. In the research of new drug candidates, the early identification of active metabolites is of critical importance in developing optimal clinical study designs and correct data interpretation. Active metabolites may possess advantages as drugs themselves (i.e., greater potency/efficacy, superior dispositional properties, improved safety profile), and there are many examples of drugs used in clinical practice that were originally observed as metabolites of other drugs.

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