Acetyltransferase Screening

Acetyltransferase is a type of transferase enzyme that transfers an acetyl group, such as histone acetyltransferases (HATs), choline acetyltransferase, chloramphenicol acetyltransferase and serotonin N-acetyltransferase. Among them, histone acetyltransferases (HATs) are the most important. These enzymes play a critical role in epigenetic regulation of gene expression. Besides, a potential role of HATs in the pathology of cancer, asthma, COPD and viral infection has been described (Dekker FJ et al. 2009). For example, p300 behaves as a classical tumor suppressor gene (Gayther SA et al. 2000); While, GCN5 plays a key role in EGF-mediated gene transcription and provides a target for the downregulation of oncogenic EGF signaling (Cheung P et al. 2000). These results indicate that the HATs might be exploited as anticancer targets and the specific HAT inhibitors might be potential tools for pharmacological research.

		From	To	From	To	From	To
Monday	Open	9:00am	5:00pm
Tuesday	Open	9:00am	5:00pm
Wednesday	Open	9:00am	5:00pm
Thursday	Open	9:00am	5:00pm
Friday	Open	9:00am	5:00pm
Saturday	Open	9:00am	5:00pm
Sunday	Open