NY
7,171 RESULTS WITHIN anywhere FROM https:, United States
Distance: 12,798.63km
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
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Chiral synthesis (enantioselective synthesis also called asymmetric synthesis) is the synthesis of a compound by a method that favors the formation of a specific enantiomer or diastereomer. It is a key process in modern chemistry and is particularly important in the field of medicinal chemistry as the different enantiomers or diastereomers of a molecule often have different biological activity. BOC Sciences has assembled a world-class team of experts to bring extensive experience in diastereoselective and enantioselective synthesis at very large scale. We provide all the services like asymmetric catalysis chiral auxiliaries biocatalysis enantioselective organocatalysis chiral pool synthesis and chiral resolution... read more
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Chiral synthesis (enantioselective synthesis also called asymmetric synthesis) is the synthesis of a compound by a method that favors the formation of a specific enantiomer or diastereomer. It is a key process in modern chemistry and is particularly important in the field of medicinal chemistry as the different enantiomers or diastereomers of a molecule often have different biological activity. BOC Sciences has assembled a world-class team of experts to bring extensive experience in diastereoselective and enantioselective synthesis at very large scale. We provide all the services like asymmetric catalysis chiral auxiliaries biocatalysis enantioselective organocatalysis chiral pool synthesis and chiral resolution... read more
Distance: 12,798.63km
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Tel:
Antibody-drug conjugates (ADCs) are a very important class of highly potent drugs designed as a targeted therapy for the treatment of people who has cancer. It represents an innovative therapeutic application that includes the unique high specificity and antitumor activity of monoclonal antibodies which are tumor-specific but not very cytotoxic with the cell killing activity of small molecule drugs that are too toxic to be used on their own. Scientists could optimize the features of both components by linking monoclonal antibodies with cytotoxic agents. BOC Sciences is the industry leading expert in small molecular and antibody engineering also our rich... read more
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Antibody-drug conjugates (ADCs) are a very important class of highly potent drugs designed as a targeted therapy for the treatment of people who has cancer. It represents an innovative therapeutic application that includes the unique high specificity and antitumor activity of monoclonal antibodies which are tumor-specific but not very cytotoxic with the cell killing activity of small molecule drugs that are too toxic to be used on their own. Scientists could optimize the features of both components by linking monoclonal antibodies with cytotoxic agents. BOC Sciences is the industry leading expert in small molecular and antibody engineering also our rich... read more
Distance: 12,798.63km
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Tel:
At BOC Sciences our expertise in multi-disciplinary sciences offers integration drug discovery services to our clients in pharmaceutical industries small business and research institutes across the world. We are here to help you discovering and characterizing novel drug candidates for preclinical development from hit ID to IND. Our experienced expertise in total synthesis and methodology development delivers data-driven research in innovative and reliable science you can trust to progress your drug discovery programs.... read more
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At BOC Sciences our expertise in multi-disciplinary sciences offers integration drug discovery services to our clients in pharmaceutical industries small business and research institutes across the world. We are here to help you discovering and characterizing novel drug candidates for preclinical development from hit ID to IND. Our experienced expertise in total synthesis and methodology development delivers data-driven research in innovative and reliable science you can trust to progress your drug discovery programs.... read more
Distance: 12,798.63km
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Superparamagnetic iron oxide microbeads have broad applications in biomedicine such as magnetic cell isolation and biomolecules purification magnetic resonance imaging of diseased tissues magnetic immunoassay targeted delivery of drugs and antigens hyperthermia aided chemo/radiotherapy and so on. BOC Sciences offers high-quality superparamagnetic iron oxide microbeads. Our products include various-sized magnetic beads with different coupling groups for the conjugation of biomolecules. We have established a high-level platform that involves many scientists and a full set of instruments to guarantee the quality of our products and services and thereby help to facilitate your researches.... read more
Superparamagnetic iron oxide microbeads have broad applications in biomedicine such as magnetic cell isolation and biomolecules purification magnetic resonance imaging of diseased tissues magnetic immunoassay targeted delivery of drugs and antigens hyperthermia aided chemo/radiotherapy and so on. BOC Sciences offers high-quality superparamagnetic iron oxide microbeads. Our products include various-sized magnetic beads with different coupling groups for the conjugation of biomolecules. We have established a high-level platform that involves many scientists and a full set of instruments to guarantee the quality of our products and services and thereby help to facilitate your researches.... read more
Distance: 12,798.63km
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Tel:
Organic fluorine compounds have had a profound impact on the development of bioactive for the modern pharmaceuticals market. It is estimated that up to 20% of pharmaceuticals prescribed or administered in the clinic contain a fluorine atom and 30% of the leading 30 blockbuster drugs by sales contain a fluorine. BOC Sciences has major skills and a high degree of expertise in the field of fluorinated organic and inorganic chemicals providing a creative and innovative range of building blocks reagents and compressed and liquefied gases. Using fluorination technology that is our specialty BOC Sciences offers contract manufacturing of fluorinated compounds... read more
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Organic fluorine compounds have had a profound impact on the development of bioactive for the modern pharmaceuticals market. It is estimated that up to 20% of pharmaceuticals prescribed or administered in the clinic contain a fluorine atom and 30% of the leading 30 blockbuster drugs by sales contain a fluorine. BOC Sciences has major skills and a high degree of expertise in the field of fluorinated organic and inorganic chemicals providing a creative and innovative range of building blocks reagents and compressed and liquefied gases. Using fluorination technology that is our specialty BOC Sciences offers contract manufacturing of fluorinated compounds... read more
Distance: 12,798.63km
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Tel:
The linker that connects the cytotoxic drug to the mAb is a key determinant of ADC activity. These linkers covalently couple the cytotoxic drug to the antibody producing an ADC that should be relatively stable in circulation. Stability of the linker is important because it prevents damage to nontarget tissue through spontaneous release of the cytotoxic drug while maximizing tumor drug exposure. Upon internalization however the linkers should facilitate efficient drug release. Intracellular conditions such as the low-pH environment in lysosomes or the reducing environment of the cytosol can destabilize acid-labile hydrazone linkers or disulfide-based linkers respectively resulting in drug... read more
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The linker that connects the cytotoxic drug to the mAb is a key determinant of ADC activity. These linkers covalently couple the cytotoxic drug to the antibody producing an ADC that should be relatively stable in circulation. Stability of the linker is important because it prevents damage to nontarget tissue through spontaneous release of the cytotoxic drug while maximizing tumor drug exposure. Upon internalization however the linkers should facilitate efficient drug release. Intracellular conditions such as the low-pH environment in lysosomes or the reducing environment of the cytosol can destabilize acid-labile hydrazone linkers or disulfide-based linkers respectively resulting in drug... read more
Distance: 12,798.63km
45-16 Ramsey Road, Shirley, NY 11967, USA, Shirley, NY
Immune checkpoints are proteins in the immune system that either turn up a signal or turn down a signal. These proteins help keep immune responses in check and can keep T cells from killing cancer cells. When these proteins are blocked the “brakes†on the immune system are released and T cells are able to kill cancer cells better. The main types of immunotherapy can be broadly subdivided into non-antigen-specific and antigen-specific categories. Non-antigen-specific strategies include nonspecific immune stimulation and Immune checkpoint inhibitors whereas antigen-specific strategies include adoptive cell transfer of autologous cancer-specific T cells and various therapeutic vaccination approaches.... read more
Immune checkpoints are proteins in the immune system that either turn up a signal or turn down a signal. These proteins help keep immune responses in check and can keep T cells from killing cancer cells. When these proteins are blocked the “brakes†on the immune system are released and T cells are able to kill cancer cells better. The main types of immunotherapy can be broadly subdivided into non-antigen-specific and antigen-specific categories. Non-antigen-specific strategies include nonspecific immune stimulation and Immune checkpoint inhibitors whereas antigen-specific strategies include adoptive cell transfer of autologous cancer-specific T cells and various therapeutic vaccination approaches.... read more
Distance: 12,798.63km
Clarence New York, Clarence
Tel: (716) 602-8344
Dave The Cabinet Guy Working form Number of years and providing Kitchen Design Service Kitchen Remodeling Service and also Supply Kitchen Cabinets.We are Serving in Clarence New York. Ready to Assemble Cabinets and Shaker style kitchen Cabinets we will help you to design your kitchen with new look and style. Contact Us for more information (716) 602-8344 Email: [email protected]... read more
Tel: (716) 602-8344
Dave The Cabinet Guy Working form Number of years and providing Kitchen Design Service Kitchen Remodeling Service and also Supply Kitchen Cabinets.We are Serving in Clarence New York. Ready to Assemble Cabinets and Shaker style kitchen Cabinets we will help you to design your kitchen with new look and style. Contact Us for more information (716) 602-8344 Email: [email protected]... read more
Distance: 12,798.63km
1500 Market Street, 12th Floor, Philadelphia, PA 19102, Philadelphia
Tel: 855-678-7452
Attorneysinarush.com is the largest and richest database of expert legal attorneys throughout the country categorized in a composed and user-friendly method enabling clients to choose easily. This is a superior search based web platform providing the fundamental as well as crucial information of the attorneys to the clients. A client can thoroughly scout through the various profiles based on the practice area jurisdictions admitted to practice professional experience and professional associations. A client based in Philadelphia can promptly contact a Criminal Lawyer Edison NJ and receive expedite legal counsel if necessary just within eight business hours or even less at... read more
Tel: 855-678-7452
Attorneysinarush.com is the largest and richest database of expert legal attorneys throughout the country categorized in a composed and user-friendly method enabling clients to choose easily. This is a superior search based web platform providing the fundamental as well as crucial information of the attorneys to the clients. A client can thoroughly scout through the various profiles based on the practice area jurisdictions admitted to practice professional experience and professional associations. A client based in Philadelphia can promptly contact a Criminal Lawyer Edison NJ and receive expedite legal counsel if necessary just within eight business hours or even less at... read more
Distance: 12,798.63km
Manhattan NY, Manhattan
Tel: 212-222-8450
We provide custom gates for your residential and commercial properties to enhance the security. You Can contact for gates fire escape repair provide you 24/7 services in Manhattan and Surrounding area's. We are providing these Services : Security Gates Steel Railings Steel Trap Doors Ironworks Metal Gates Repair AC BoxesTree Guards Iron Railings Welding Repairs Contact for more information and detail : 212-222-8450... read more
Tel: 212-222-8450
We provide custom gates for your residential and commercial properties to enhance the security. You Can contact for gates fire escape repair provide you 24/7 services in Manhattan and Surrounding area's. We are providing these Services : Security Gates Steel Railings Steel Trap Doors Ironworks Metal Gates Repair AC BoxesTree Guards Iron Railings Welding Repairs Contact for more information and detail : 212-222-8450... read more
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