Introduction
c-Kit
Mast/stem cell growth factor receptor (SCFR), also known as proto-oncogene c-Kit or tyrosine-protein kinase Kit or CD117, is a receptor protein-tyrosine kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays important roles in gametogenesis, hematopoiesis, mast cell development and function, and melanogenesis. c-Kit consists of an extracellular domain, a transmembrane segment, a juxtamembrane segment, and a protein kinase domain that contains an insert of about 80 amino acid residues. Binding of stem cell factor to Kit results in receptor dimerization and activation of protein kinase activity.
Catalog Product Name CAS Number
1048007-93-7Masitinib mesylate1048007-93-7
1123837-84-2Sitravatinib1123837-84-2
B0084-457687DCC-26181225278-16-9
152459-95-5Imatinib152459-95-5
B0084-007732Avapritinib1703793-34-3
220127-57-1Imatinib Mesylate220127-57-1
B0084-313239SU11652326914-10-7
B0084-108953Telatinib332012-40-5
B0084-091881Dovitinib405169-16-6
B0084-069090Motesanib453562-69-1
B0084-077384Masitinib790299-79-5
850879-09-3Amuvatinib850879-09-3
B0084-153042Motesanib Diphosphate857876-30-3
B0084-474894Flumatinib895519-90-1
ISCK03945526-43-2
Mast/stem cell growth factor receptor (SCFR), also known as proto-oncogene c-Kit or tyrosine-protein kinase Kit or CD117, is a receptor protein-tyrosine kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays important roles in gametogenesis, hematopoiesis, mast cell development and function, and melanogenesis. c-Kit consists of an extracellular domain, a transmembrane segment, a juxtamembrane segment, and a protein kinase domain that contains an insert of about 80 amino acid residues. Binding of stem cell factor to Kit results in receptor dimerization and activation of protein kinase activity.
Catalog Product Name CAS Number
1048007-93-7Masitinib mesylate1048007-93-7
1123837-84-2Sitravatinib1123837-84-2
B0084-457687DCC-26181225278-16-9
152459-95-5Imatinib152459-95-5
B0084-007732Avapritinib1703793-34-3
220127-57-1Imatinib Mesylate220127-57-1
B0084-313239SU11652326914-10-7
B0084-108953Telatinib332012-40-5
B0084-091881Dovitinib405169-16-6
B0084-069090Motesanib453562-69-1
B0084-077384Masitinib790299-79-5
850879-09-3Amuvatinib850879-09-3
B0084-153042Motesanib Diphosphate857876-30-3
B0084-474894Flumatinib895519-90-1
ISCK03945526-43-2
Contact Info
Address:
45-16 Ramsey Road, Shirley, NY 11967, USA
Shirley, NY
New York 11967
United States
Shirley, NY
New York 11967
United States
Tel:
Website:
https://www.bocsci.com/tag/c-kit-111.html
Hours of operation
| From | To | From | To | From | To | ||
|---|---|---|---|---|---|---|---|
| Monday | Open | ||||||
| Tuesday | Open | ||||||
| Wednesday | Open | ||||||
| Thursday | Open | ||||||
| Friday | Open | ||||||
| Saturday | Open | ||||||
| Sunday | Open | ||||||
